Tired of getting skunked and need some help.

My brother and I regularly try to fish this area of creek down the road from us in Gulf Coast Alabama. This little hole is upside down T Shape, about 30ft at its widest and 80 ft at its longest with a 10 ft gap down the middle. Its regularly about 4 to 6 feet deep. It passes through a drainage ditch under a dirt road and empties out into a small pond with brush forming a dam before trickling into a marsh. On sunny days we can see the bottom pretty well. I KNOW there are fish in here. Theres evidence of other anglers as well. I started to think otherwise however I saw a large Bowfin Catfish (I believe) one day, and weve been back maybe 8 times since, getting skunked for several hours each time. We have thrown the entire tacklebox at it, trying chicken, cheese,bread, cornbait, a mix of those; texas rigged worms of various varieties, small jighead lures, large crawfish lures, lizards, yomamotos and zooms. I hate for this to be a what would you throw post, but we have tried everything. Im hoping someone here has been in a similar spot and could advise us on what finally worked for them. My brother has a disability so id really like for this to be worthwhile for him, as its a task in itself to get him here.